FAS Signaling Pathway(CD95)

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FAS

FAS-L

FAS

DAXX

FAS

FAF

FAS

FADD

FASLG

FAS

JUN

JNK1

CAD

ICAD

CAD

DNA Fragmentation

RB1

PARP

RB1

CASPASE3

LMNA

LAMINb1

LMNA

LAMINb2

LMNA

CASPASE6

LMNB2

LMNB1

LMNB2

CASPASE6

FAP

FAF

FAP

PRO-CASPASE8 Complex

FAP

I-FLICE

LMNB1

LANA

LMNB1

LMNB2

LMNB1

CASPASE6

CASP3

CASP6

CASP3

PAK1-PAK2 Complex

CASP3

PARP

CASP7

CASP8

CASP7

CASP10

CASP7

MEKK1

CASP8

CASP3

CASP8

CASP7

CASP8

PRO-CASPASE Complex

CASP10

FADD

CASP10

CASP7

FADD

FAF

FADD

DAXX

FADD

FAS

FAF

FADD

FAF

FAS

FAF

FAP

DAXX

FAS

DAXX

FADD

DAXX

JNKK1

PAK1

PAK2

PAK1

MEKK1

PAK1

CASPASE3

PAK2

PAK1

PAK2

MEKK1

RIPK2

I-FLICE

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